Clinical Trial

Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease

Study acronym: DCB_DES
Not Yet Recruiting
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Record status
This record was last updated March 2, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
Studies exploring the feasibility of drug-eluting balloon (DCB) in de-novo coronary lesions are limited. There are scarce data comparing DCB with drug-eluting stent (DES) in patients with high bleeding risk (HBR), a situation in which long-term maintenance of dual antiplatelet therapy (DAPT) is a clinical dilemma. This target trial emulation aims to compare clinical outcomes between DCB angioplasty and conventional DES implantation in de-novo coronary lesions in patients with coronary artery disease.
Trial Details
NCT Number NCT07442500
Lead Sponsor Samsung Medical Center
Conditions Coronary Artery Disease, Percutaneous Coronary Intervention (PCI)
Enrollment 470,000 participants
Start Date 2026-02-28
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-02