Patient-Reported Sleep vs Objective Sleep and Physical Activity Measures in Ankylosing Spondylitis: A Pre-Post Study

Eighteen patients with active ankylosing spondylitis were evaluated at initiation of anti-TNF-α therapy and again after 4 months. Subjective sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI). Objective sleep parameters were measured by overnight polysomnography, and physical activity was assessed using a multi-sensor wearable accelerometer. Clinical outcomes included BASDAI/BASFI, ASQoL, and HADS. This was a prospective, single-arm pre-post pilot study

NCT Number	NCT07441239
Lead Sponsor	Samsun University
Conditions	Ankylosing Spondylitis (AS), Sleep Quality, Physical Activity
Enrollment	18 participants
Start Date	2015-08-01
Primary Completion	2016-10-31 (estimated)
Study Completion	2016-10-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-27