Aerobic Reconditioning After Cardiac Surgery Using a Predictive Exercise Model

Brief Summary After heart surgery, aerobic exercise is essential for recovery. Traditional exercise planning uses a cardiopulmonary exercise test (CPET), which may be unavailable early after surgery. This study tested a six-minute walk test (6MWT)-based method. Patients aged 30-65 were randomized to either 6MWT-guided or symptom-guided exercise. They completed 14 supervised cycling sessions over two weeks. Safety, exercise progression, training volume, functional capacity, physical performance, and quality of life were measured. Out of 118 patients, 109 completed the program with no serious exercise-related events. The 6MWT group started at higher intensity and achieved greater training volume. Both groups improved similarly in functional and quality-of-life measures, showing the 6MWT method is safe, feasible, and non-inferior to the traditional approach.

NCT Number	NCT07440407
Lead Sponsor	Istituti Clinici Scientifici Maugeri SpA
Conditions	Post-cardiac Surgery, Rehabilitation
Enrollment	118 participants
Start Date	2022-03-30
Primary Completion	2024-04-30 (estimated)
Study Completion	2024-07-15 (estimated)
Updated on ClinicalTrials.gov	2026-03-03