Clinical Trial

Optimized Strict Fluid Management Helps Improve Endpoints After Liver Dissection

Study acronym: SHIELD-pilot
Not Yet Recruiting
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Summary
During hepatectomy, surgeons often prefer to restrict fluid intake, believing that this can lower central venous pressure (CVP) and reduce intraoperative blood loss. However, fluid restriction may lead to inadequate perfusion of vital organs and even contribute to postoperative organ dysfunction, such as acute kidney injury (AKI). Therefore, this study aims to compare the effects of restrictive versus liberal fluid therapy on major complications following hepatectomy.
Trial Details
NCT Number NCT07440121
Lead Sponsor Zhihong LU
Conditions Anesthesia, Surgery
Enrollment 90 participants
Start Date 2026-04-02
Primary Completion 2026-12-02 (estimated)
Study Completion 2027-02-02 (estimated)
Updated on ClinicalTrials.gov 2026-02-27