Clinical Trial

Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery

Study acronym: IMPROVE-8
Not Yet Recruiting
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Summary
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily fish or from supplements. The Index reflects long-term Omega-3 intake and is considered optimal at 8% or higher. Levels below this range have been linked with poorer cardiovascular health (Harris \& Von Schacky, 2004). . For athletes, Omega-3 research suggests they can help reduce inflammation, ease muscle soreness, and support immune function. Despite this, many elite athletes appear to have Omega-3 Index values around 4-5%, well below the recommended level of 8%. Therefore, the aim of this study is to investigate whether increasing the Omega-3 index has any recovery benefits post a bout of downhill running in athletes. Downhill running is commonly used as way to cause exercise-induced muscle damage and study recovery. The Omega-3 index will be increased with a daily fish oil supplement.
Trial Details
NCT Number NCT07439601
Lead Sponsor St. Mary's University, Twickenham
Conditions Focus on Omega 3 Index on Recovery
Enrollment 46 participants
Start Date 2026-02-28
Primary Completion 2027-12-30 (estimated)
Study Completion 2028-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-27