Clinical Trial

Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study

Study acronym: US-SCAR-PAIN
Not Yet Recruiting
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Record status
This record was last updated February 27, 2026 (before its estimated May 23, 2026 completion). Its status may not reflect the trial's current state.
Summary
Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue. This prospective cohort study aims to determine whether early ultrasound features of scars and nerves predict persistent clinically significant scar pain at 3 and 6 months. Ultrasound measures include scar thickness, echogenicity, Power Doppler vascularity, dynamic adhesion (gliding) assessment, and ultrasound signs of nerve involvement ("US-nerve positive"). Clinical outcomes include pain intensity (NRS), neuropathic pain screening (DN4), and functional interference.
Trial Details
NCT Number NCT07438769
Lead Sponsor Ukrainian Society of Regional Anesthesia and Pain Therapy
Conditions Burn Scar Pain, Neuropathic Pain, Combat-Related Burn Injury, Scar-Related Pain
Enrollment 150 participants
Start Date 2026-03-24
Primary Completion 2026-05-23 (estimated)
Study Completion 2026-05-23 (estimated)
Updated on ClinicalTrials.gov 2026-02-27