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Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study

Study acronym: US-SCAR-PAIN
StatusNot Yet Recruiting
PhaseNot specified
Started
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Record status
This record was last updated February 27, 2026 (before its estimated May 23, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue. This prospective cohort study aims to determine whether early ultrasound features of scars and nerves predict persistent clinically significant scar pain at 3 and 6 months. Ultrasound measures include scar thickness, echogenicity, Power Doppler vascularity, dynamic adhesion (gliding) assessment, and ultrasound signs of nerve involvement ("US-nerve positive"). Clinical outcomes include pain intensity (NRS), neuropathic pain screening (DN4), and functional interference.
Trial Details
NCT Number NCT07438769
Lead Sponsor Ukrainian Society of Regional Anesthesia and Pain Therapy
Conditions
(from sponsor)		 Burn Scar Pain, Neuropathic Pain, Combat-Related Burn Injury, Scar-Related Pain
Related terms Blast Injuries, Nerve Compression Syndromes, Neuralgia
Enrollment 150 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov