Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain

Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the combination of PIP block and ESPB in patients undergoing modified radical mastectomy for reducing acute and chronic post mastectomy pain

NCT Number	NCT07438366
Lead Sponsor	South Egypt Cancer Institute Collaborators: Assiut University
Conditions	Post-mastectomy Pain Syndrome
Enrollment	60 participants
Start Date	2026-02-15
Primary Completion	2026-11-01 (estimated)
Study Completion	2027-02-15 (estimated)
Updated on ClinicalTrials.gov	2026-02-27