Clinical Trial

Clinical Efficacy and Survival Prediction Analysis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver Cirrhosis

Active, Not Recruiting
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Record status
This record was last updated February 27, 2026 (before its estimated April 5, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to develop a practical tool for identifying cirrhotic patients at high risk of hepatic encephalopathy following transjugular intrahepatic portosystemic shunt (TIPS) placement. A retrospective analysis will be conducted on medical records of 624 cirrhotic patients who underwent TIPS from 2011 to 2021. Statistical methods will be applied to screen preoperative routine indicators associated with post-TIPS hepatic encephalopathy risk. A predictive nomogram will be constructed incorporating the screened indicators to estimate individual preoperative risk. The predictive performance will be compared with conventional clinical scoring systems. This tool is intended to facilitate preoperative risk evaluation and targeted management of high-risk patients undergoing TIPS
Trial Details
NCT Number NCT07437638
Lead Sponsor The Second Affiliated Hospital of Chongqing Medical University
Conditions Liver Cirrhosis, Hepatic Encephalopathy, TIPS
Enrollment 624 participants
Start Date 2024-09-01
Primary Completion 2026-04-05 (estimated)
Study Completion 2026-04-05 (estimated)
Updated on ClinicalTrials.gov 2026-02-27