Relation Between Muscle Architecture and Functional Ability in Children With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is a progressive X-linked neuromuscular disorder characterized by muscle degeneration, pseudohypertrophy, and declining functional mobility. This cross-sectional observational study investigates the relationship between gastrocnemius muscle architecture and functional ability in ambulatory children with DMD. Muscle thickness and fascicle length were assessed using ultrasonography and correlated with motor function and ankle plantarflexion during gait.

NCT Number	NCT07437378
Lead Sponsor	Deraya University
Conditions	Duchenne Muscular Dystrophy (DMD), Neuromuscular Disorders, Muscle Architecture
Enrollment	26 participants
Start Date	2024-09-10
Primary Completion	2025-10-31 (estimated)
Study Completion	2025-11-10 (estimated)
Updated on ClinicalTrials.gov	2026-02-27