Clinical Trial

CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

Study acronym: CHEST-CA
Recruiting
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Summary
The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.
Trial Details
NCT Number NCT07435168
Lead Sponsor Rigshospitalet, Denmark
Conditions Cardiac Amyloidosis, Chest Pain
Enrollment 300 participants
Start Date 2024-04-01
Primary Completion 2027-04-01 (estimated)
Study Completion 2027-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-27