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Orthobiological Therapies in Musculoskeletal Disorders

Study acronym: PROREGEN
StatusRecruiting
PhaseEarly Phase 1
SponsorPROREGEN
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Recruitment opened
    • Start date changed from estimate of Jan 30, 2026 to Sep 16, 2026
    • Eligibility criteria expanded, about 10 words
    • Publications: details revised at 3 of 3 entries
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
To evaluate the clinical and functional effects of using orthobiological therapies (hyaluronic acid, platelet-rich plasma, bone marrow aspirate, nanofat, among others) in the treatment of various musculoskeletal diseases in patients routinely treated at the Proregen Medical Clinic and its affiliates. The sample will consist of adult patients (≥18 years), of both sexes, with different musculoskeletal diagnoses involving joints, tendons, ligaments, cartilage or bone, among others.
Trial Details
NCT Number NCT07434115
Lead Sponsor PROREGEN
Collaborators: Centro Universitário Univates
Conditions
(from sponsor)		 Musculoskeletal Diseases or Conditions
Related terms Musculoskeletal Diseases
Enrollment 300 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov