Clinical Trial

Prefrontal Neuroplasticity and Coping Strategies in Healthy Population

Completed
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Summary
The current study serves as a pilot for the GRF project "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS." The project examines whether intermittent theta-burst stimulation (iTBS) induces immediate changes in prefrontal excitability in healthy individuals, compared to sham stimulation. In this randomized, sham-controlled trial, investigators will assess several psychological measures-including the Perceived Stress Scale and the Coping Inventory for Stressful Situations-to explore how stress levels and coping strategies relate to immediate prefrontal cortex (PFC) activity changes following TBS.
Protocol Amendment History 2 changes
critical Trial completed 2026-06-27
notable Enrollment increased: 32 -> 42 participants 2026-04-03
Trial Details
NCT Number NCT07433829
Lead Sponsor The Hong Kong Polytechnic University
Conditions Health Adult Subjects
Enrollment 40 participants
Start Date 2026-01-17
Primary Completion 2026-03-31 (estimated)
Study Completion 2026-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-06-26