Clinical Trial

Kinematics-Based Prediction of Chronic Pain After Combat-Related Extremity Trauma

Study acronym: KIN-LIMB
Enrolling by Invitation
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Summary
Combat-related extremity trauma frequently results in persistent pain, including neuropathic, residual limb, and phantom limb pain. The kinematics of injury-including energy level, direction of force, and dominant force components-may independently predict tissue deformation, nerve stress, and the transition from acute to chronic- pain. This prospective observational cohort study will assess whether kinematics-only variables predict chronic pain outcomes after combat-related upper and lower limb injuries. Pain outcomes will include pain intensity, pain extent (surface/area), neuropathic pain features, and mechanical pain sensitivity measured using von Frey filaments.
Trial Details
NCT Number NCT07432685
Lead Sponsor Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Conditions Residual Limb Pain, Post-Traumatic Limb Pain, Extremity Trauma, Combat-Related Limb Injury, Phantom Limb Pain, Phantom Limb Pain After Amputation, Chronic Pain Due to Injury, Chronic Pain
Enrollment 100 participants
Start Date 2026-03-12
Primary Completion 2026-12-22 (estimated)
Study Completion 2027-12-14 (estimated)
Updated on ClinicalTrials.gov 2026-02-25