Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass

This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.

NCT Number	NCT07432477
Lead Sponsor	Ondokuz Mayıs University
Conditions	Atelectasis, Postoperative
Enrollment	52 participants
Start Date	2026-02-15
Primary Completion	2027-02-01 (estimated)
Study Completion	2027-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-01