Clinical Trial

Detecting Clinically Significant Prostate Cancer With Advanced MRI Protocols and Extensive Histopathology

Recruiting
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Summary
In recent years, new and promising approaches have emerged in the field of MRI imaging of the prostate. These approaches usually aim to visualise the so-called "microstructures" of the tissue and are intended to offer greater accuracy in the diagnosis of prostate cancer than the current mpMRI examination. To this end, mathematical microstructure models are calculated that determine the proportional presence of histological substructures in specific MRI volumes. Additional new MRI sequences that are not routinely recorded are required to calculate the microstructure models. In order to further investigate the possibilities of these new MRI sequences, this study will compare different mathematical models. In addition, a histopathological examination of the tissue will be performed.
Trial Details
NCT Number NCT07432360
Lead Sponsor Virdx, Inc.
Collaborators: Instituto do Cancer do Estado de São Paulo
Conditions Prostate Cancer
Enrollment 300 participants
Start Date 2026-01-28
Primary Completion 2028-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-02-25