Clinical Trial

The AIR-CPR Study: AI-Guided Chest Compressions

Study acronym: AIR-CPR
Recruiting
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Summary
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations. Current guidelines recommend a standardized compression point (the lower half of the sternum), yet recent research indicates that this position can compress the aortic valve in approximately 48.7% of patients, significantly reducing the chances of successful resuscitation. This study will develop a deep learning model based on YOLO v8 to analyze real-time arterial pressure waveforms to identify proper aortic valve opening and closing. By identifying specific waveform features that humans cannot easily distinguish, the AI will guide rescuers to adjust the compression site-typically toward the left ventricle-to ensure optimal blood output. The project seeks to transform CPR from a standardized "one-size-fits-all" approach into a personalized, precision medicine intervention.
Trial Details
NCT Number NCT07431710
Lead Sponsor Far Eastern Memorial Hospital
Collaborators: National Health Research Institutes, Taiwan
Conditions Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
Enrollment 255 participants
Start Date 2025-01-06
Primary Completion 2027-12-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-24