Sense of Coherence and Quality of Life in Prostate Cancer Patients Treated With Radical Radiotherapy

This prospective single-group interventional study evaluates the relationship between sense of coherence (SOC), health-related quality of life (HRQL), and self-rated health (SRH) in patients with prostate cancer treated with radical radiotherapy. The study aims to identify factors that may contribute to improved quality of life and coping after treatment. Participants complete validated questionnaires assessing HRQL (EORTC QLQ-C30), SOC (SOC-13), and self-rated health at predefined time points. In addition, objectively assessed treatment-related problems are evaluated using a structured physician-led interview. Data are collected before the start of radiotherapy, at the end of radiotherapy, and one year after completion of treatment.

NCT Number	NCT07431684
Lead Sponsor	Institute of Oncology Ljubljana
Conditions	Prostate Cancer
Enrollment	250 participants
Start Date	2021-09-01
Primary Completion	2023-09-01 (estimated)
Study Completion	2026-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-03