Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste

This randomized, examiner-blind, parallel-group clinical study evaluated the effectiveness of a whitening toothpaste compared with a control toothpaste in removing extrinsic tooth stain over six weeks of twice-daily unsupervised use. Adult subjects were assessed at baseline and after 7, 14, 28, and 42 days of product use using the Macpherson Modification of the Lobene Stain Index. Oral soft and hard tissues and subject-reported sensory responses were also evaluated throughout the study.

NCT Number	NCT07428603
Lead Sponsor	Church & Dwight Company, Inc.
Conditions	Stain Removal Efficacy
Enrollment	118 participants
Start Date	2024-08-08
Primary Completion	2024-09-20 (estimated)
Study Completion	2024-09-20 (estimated)
Updated on ClinicalTrials.gov	2026-02-24