Cortical Changes After Upper Limb Immobilization Measured by Electroencephalography

This study aims to investigate how temporary immobilization of the upper limb after injury affects brain activity and functional recovery. Participants with fractures or soft tissue injuries of the upper limb who require immobilization will be evaluated at three time points: at the beginning of immobilization, after removal of the immobilization, and four weeks later. Brain activity will be measured using electroencephalography (EEG), a non-invasive and painless technique that records electrical signals from the scalp. Functional outcomes such as pain, mobility, strength, and daily activity performance will also be assessed using validated questionnaires and clinical tests. The purpose of this study is to better understand how immobilization influences the brain and physical recovery, in order to improve rehabilitation strategies for patients with upper limb injuries. Participation is voluntary, and all participants will provide written informed consent.

NCT Number	NCT07428304
Lead Sponsor	University of Malaga
Conditions	Wrist Injury, Hand and Upper Limb Trauma, Muskuloskeletal Diseases
Enrollment	30 participants
Start Date	2026-04-01
Primary Completion	2026-12-31 (estimated)
Study Completion	2027-02-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-03