Regenerative Endodontics of Immature Teeth in Multiple Visits Versus Single Visit

This randomized clinical trial evaluated the clinical and radiographic outcomes of regenerative endodontic procedures performed using different irrigation activation protocols in immature permanent maxillary anterior teeth. Thirty patients were randomly assigned into three groups according to the use of laser-activated irrigation and number of visits. Clinical and cone beam computed tomographic (CBCT) outcomes were assessed over a 12-month follow-up period.

NCT Number	NCT07427615
Lead Sponsor	Ahmed Ibrahim Salim
Conditions	Regenerative Endodontic Procedures
Enrollment	30 participants
Start Date	2023-03-01
Primary Completion	2024-11-29 (estimated)
Study Completion	2025-11-29 (estimated)
Updated on ClinicalTrials.gov	2026-02-23