Chronic Kidney Disease Associated Diet

The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the Dietary Inflammatory Index (DII), in this association. The main question it aims to answer is: Does a pro-inflammatory diet, as reflected by a higher DII score, exacerbate periodontal inflammation in individuals with chronic kidney disease? Participants will include adults diagnosed with CKD at various stages. Periodontal status will be assessed through clinical parameters such as probing depth, clinical attachment loss, and bleeding on probing. Dietary intake will be evaluated using a validated food frequency questionnaire, and DII scores will be calculated accordingly. The study will aim to observe and analyze whether dietary inflammation contributes to increased periodontal disease severity in CKD patients, potentially offering insight into modifiable risk factors relevant to both systemic and oral health.

NCT Number	NCT07427069
Lead Sponsor	Recep Tayyip Erdogan University Training and Research Hospital
Conditions	Chronic Kidney Disease, Periodontitis, Diet, Food and Nutrition
Enrollment	100 participants
Start Date	2026-04-20
Primary Completion	2026-10-19 (estimated)
Study Completion	2026-11-16 (estimated)
Updated on ClinicalTrials.gov	2026-02-24