Clinical Trial

Vaginal Cuff Bupivacaine Injection for Postoperative Pain

Study acronym: marcaine
Completed
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Summary
This randomized controlled study evaluates whether injecting bupivacaine into the vaginal cuff during vaginal hysterectomy reduces postoperative pain. Vaginal hysterectomy is commonly performed for benign gynecologic conditions. Although it is associated with less pain compared to abdominal surgery, postoperative discomfort may still affect recovery and patient satisfaction. In this study, 48 women undergoing elective vaginal hysterectomy were randomly assigned to two groups. In the intervention group, 0.25% bupivacaine was injected bilaterally into the vaginal cuff after closure. In the control group, no local anesthetic injection was administered. All patients received the same standard postoperative pain management protocol. Pain levels were measured using the Visual Analog Scale (VAS) at 1, 3, 6, 12, and 24 hours after surgery. Additional analgesic consumption and possible complications were also recorded. The study aims to determine whether vaginal cuff bupivacaine infiltration improves early postoperative pain control.
Trial Details
NCT Number NCT07426666
Lead Sponsor Havva Betül Bacak
Conditions Postoperative Pain Management
Enrollment 48 participants
Start Date 2025-08-05
Primary Completion 2025-10-24 (estimated)
Study Completion 2025-10-24 (estimated)
Updated on ClinicalTrials.gov 2026-02-23