Clinical Trial

Evaluate the Effect of Fluoride-Releasing Composite Resin on Prevention of White Spot Lesions During Clear Aligner Therapy

Active, Not Recruiting
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Record status
This record was last updated February 23, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Aim of this study: evaluate the effect of fluoride-releasing composite resin as attachments on prevention of white spot lesions. Material and methods: Type: Prospective, randomized split mouth controlled study. Interventions: Intervention Group (Experimental Side): •Application of fluoride-releasing composite Control Group (Control Side): •Application of conventional composite Outcome Measures: Primary Outcome: Incidence and Severity of White Spot Lesions Secondary Outcomes: 1. Periodontal Ligament (PDL) Health 2. Gingival Bleeding and Inflammation
Trial Details
NCT Number NCT07426432
Lead Sponsor Mansoura University
Conditions White Spot Lesions, Clear Aligner Appliance
Enrollment 24 participants
Start Date 2025-08-01
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-09-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-23