Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.

The purpose of this study is to investigate whether the elevated circulating lactate levels of individuals with metabolic syndrome are responsible for their reduced lipolysis and glucose tolerance. The investigators will conduct an intervention study in which blood lactate levels will be elevated via intravenous infusion of sodium lactate. State of the art metabolic assessment using stable isotopes and indirect calorimetry will be used to study alterations in fat and carbohydrate metabolism.

NCT Number	NCT07426172
Lead Sponsor	Ricardo Mora Collaborators: University of Castilla-La Mancha
Conditions	Hyperlactatemia, Metabolic Syndrome (MetS), Lipolysis, Exercise
Enrollment	24 participants
Start Date	2026-01-20
Primary Completion	2028-01-30 (estimated)
Study Completion	2028-09-30 (estimated)
Updated on ClinicalTrials.gov	2026-02-23