Clinical Trial

Investigation of the Relationship Between Gray and White Matter Volumes, Walking Exercise, and Body Fat Percentage in Adults With a Body Mass Index Above 25

Completed
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Summary
This study examines the relationship between walking exercise, body fat percentage changes, and brain gray and white matter volumes in overweight and obese adults with headache complaints. Participants with a Body Mass Index (BMI) of 25 or above will be divided into two groups: one receiving a diet program combined with a 12-week walking exercise regimen, and a control group receiving diet alone. Both groups will undergo brain MRI scans and body composition measurements at baseline and after 12 weeks. The study aims to determine whether exercise-induced reductions in body fat percentage have a measurable impact on brain structure, specifically gray and white matter volumes. Blood tests will monitor metabolic markers throughout the intervention. This research may contribute to understanding how different types of exercise affect brain health and inform the development of more effective treatments for obesity-related neurological changes.
Trial Details
NCT Number NCT07425093
Lead Sponsor Amasya University
Conditions Obesity & Overweight, Headache, Sedentary Lifestyle, Body Fat Percentage, Brain Grey Matter, Brain White Matter
Enrollment 22 participants
Start Date 2024-01-01
Primary Completion 2024-03-01 (estimated)
Study Completion 2024-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-20