Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).

NCT Number	NCT07424365
Lead Sponsor	University of Colorado, Denver
Conditions	Mild Cognitive Impairment (MCI), Parkinsons Disease (PD), Healthy Adult
Enrollment	80 participants
Start Date	2025-05-19
Primary Completion	2028-05 (estimated)
Study Completion	2028-05 (estimated)
Updated on ClinicalTrials.gov	2026-02-20