Olfactory Function and Oral Malodor in Periodontitis Before and After Periodontal Therapy

This prospective cohort study investigated the relationship between oral malodor and olfactory function in adults with generalized periodontitis. A total of 101 patients were evaluated before and after routine nonsurgical periodontal therapy. Volatile sulfur compound (VSC) levels and psychophysical olfactory performance using the Sniffin' Sticks test (TDI score) were measured at baseline and one week after completion of three sessions of scaling and root planing (SRP). The study aimed to determine whether reduction of oral inflammation and halitosis is associated with improvement in olfactory performance.

NCT Number	NCT07424300
Lead Sponsor	Batman University
Conditions	Periodontitis, Olfactory Dysfunction, Halitosis
Enrollment	101 participants
Start Date	2024-12-03
Primary Completion	2025-03-20 (estimated)
Study Completion	2025-03-20 (estimated)
Updated on ClinicalTrials.gov	2026-02-25