Clinical Trial

Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions

Active, Not Recruiting Early Phase 1
View on ClinicalTrials.gov →
Record status
This record was last updated February 20, 2026 (before its estimated March 10, 2026 completion). Its status may not reflect the trial's current state.
Summary
It is tackling antimicrobial resistance in endodontics, specifically comparing different intracanal medications used in root canal treatment. Given the growing concern over resistant bacterial strains, our study aims to evaluate the effectiveness of various medicaments in eliminating endodontic pathogens while minimising the risk of resistance development. By integrating microbiological analysis and clinical relevance, our research seeks to provide evidence-based recommendations for optimising intracanal disinfection protocols and improving treatment outcomes in endodontic infections.
Trial Details
NCT Number NCT07423663
Lead Sponsor Suez Canal University
Collaborators: University of Leeds
Conditions Asymptomatic Apical Periodontitis
Enrollment 63 participants
Start Date 2024-09-01
Primary Completion 2026-03-10 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-20