Plant-Protein Dominant Tube Feed Study

This study aims to determine whether a reformulated plant-protein dominant protein blend in four existing enteral tube feeds is as effective as animal-protein dominant formulations in patients who are tube fed at home. This is an exploratory randomised, controlled, trial with a 3-day baseline period. Adult home tube feeding patients will be randomised to receive either a plant-protein dominant formulation or a control product (an animal-protein dominant formulation) for a 3-month intervention period followed by a 6-month and 12-month follow-up. The outcomes include gastrointestinal tolerance, compliance, acceptability, anthropometry, nutrient intake, and physical function

NCT Number	NCT07422935
Lead Sponsor	Nutricia UK Ltd Collaborators: University Hospitals Coventry and Warwickshire NHS Trust, Gateshead Health NHS Foundation Trust, University Hospitals of Derby and Burton NHS Foundation Trust, Bradford Teaching Hospitals NHS Foundation Trust, University College London Hospitals, South Warwickshire NHS Foundation Trust, Birmingham Community Healthcare NHS, University Hospital Birmingham, Nottingham University Hospitals NHS Trust, NORFOLK COMMUNITY HEALTH AND CARE NHS TRUST
Conditions	Enteral Nutrition (Food for Special Medical Purposes), Enteral Feeds
Enrollment	110 participants
Start Date	2026-01-01
Primary Completion	2027-03 (estimated)
Study Completion	2027-03 (estimated)
Updated on ClinicalTrials.gov	2026-02-20