Clinical Trial

Intravenous Nalbuphine Versus Lidocaine for Prevention of Propofol Injection Pain

Not Yet Recruiting
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Record status
This record was last updated February 20, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Propofol is a commonly used intravenous anesthetic agent, but its administration is frequently associated with injection pain, causing patient discomfort and agitation. Various pharmacological agents have been used to reduce this pain, including nalbuphine and lidocaine; however, results from previous studies remain conflicting. This randomized clinical trial aims to compare the effectiveness of intravenous nalbuphine versus intravenous lidocaine in reducing the frequency of propofol-induced injection pain in patients undergoing elective general surgery procedures.
Trial Details
NCT Number NCT07422558
Lead Sponsor Hayatabad Medical Complex
Conditions Procedural Pain
Enrollment 92 participants
Start Date 2026-03-01
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-08-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-20