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Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair

Study acronym: CLOSE-STAT
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Aug 1, 2026 → Nov 1, 2026
See other at-risk trials from Swissmed Hospital

Record History

See every version on ClinicalTrials.gov ↗

  1. Recruitment opened Show 4 more changesShow less
    • Primary completion pushed from Aug 1, 2026 to Nov 1, 2026
    • Study sites: 0 to 1
    • Eligibility criteria expanded, about 8 words
    • Secondary endpoints: details revised at 3 of 3 entries
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.
Trial Details
NCT Number NCT07422441
Lead Sponsor Swissmed Hospital
Collaborators: Medical University of Gdansk
Conditions
(from sponsor)		 Hernia, Ventral, Hernia Incisional, Postoperative Complications, Respiratory Insufficiency
Related terms Hernia, Ventral, Incisional Hernia, Postoperative Complications, Respiratory Insufficiency
Enrollment 50 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov