Clinical Trial

Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair

Study acronym: CLOSE-STAT
Not Yet Recruiting
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Record status
This record was last updated February 20, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.
Trial Details
NCT Number NCT07422441
Lead Sponsor Swissmed Hospital
Collaborators: Medical University of Gdansk
Conditions Hernia, Ventral, Hernia Incisional, Postoperative Complications, Respiratory Insufficiency
Enrollment 50 participants
Start Date 2026-02-20
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-20