Acute Effects of LLLT on Pain Threshold and Pain Tolerance

Pain is defined by the International Association for the Study of Pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage." Low-Level Laser Therapy (LLLT) has gained attention as a safe, noninvasive intervention with analgesic and anti-inflammatory effects. This study examines whether a single session of LLLT can produce immediate changes in pain threshold and pain tolerance in healthy adults, compared to a sham laser control.

NCT Number	NCT07422272
Lead Sponsor	European University of Lefke
Conditions	Pain Threshold, Pain Tolerance, Acute Pain, Low-level Laser Therapy, LLLT vs Sham
Enrollment	62 participants
Start Date	2025-12-15
Primary Completion	2026-04-16 (estimated)
Study Completion	2026-04-16 (estimated)
Updated on ClinicalTrials.gov	2026-07-02