Multilevel Ecological and COM-B Determinants of Medication Adherence in Adults With Diabetes

This observational study aims to understand why some adults with diabetes find it difficult to take their medicines as prescribed. Medication adherence is essential for controlling blood sugar levels and preventing complications, yet many patients face challenges that go beyond personal motivation. The study will examine multiple factors that may influence medication-taking behavior, including patients' understanding of their medicines, beliefs about treatment, family and social support, communication with healthcare providers, and practical issues such as medicine cost, availability, and distance to care. These factors will be analyzed using a structured behavioral framework to better understand how capability, opportunity, and motivation contribute to adherence. By identifying the most important barriers and supports across different levels, this research aims to provide evidence that can guide patient-centered care strategies and improve medication adherence in diabetes management.

NCT Number	NCT07420634
Lead Sponsor	University of Malaya Collaborators: Maharishi Markendeswar University (Deemed to be University)
Conditions	Diabetes Mellitus, Diabetes Mellitus Type 2, Medication Adherence
Enrollment	220 participants
Start Date	2025-12-15
Primary Completion	2026-06-30 (estimated)
Study Completion	2026-08-30 (estimated)
Updated on ClinicalTrials.gov	2026-02-19