Clinical Trial

Dutasteride in Patients With Low Grade Non-muscle Invasive Bladder Cancer

Study acronym: DutaBCa-1
Recruiting Phase 2
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Summary
Low grade non-muscle-invasive bladder cancer (NMIBC) often recurs after treatment, requiring repeated surgeries, especially in older patients. These recurrences can cause complications, reduce quality of life, and increase healthcare costs. Currently, there is no well-tolerated preventive treatment routinely used for patients with low-risk disease. This study will evaluate whether dutasteride, an oral medication that blocks androgen activity, can reduce the risk of bladder cancer recurrence. Dutasteride is generally well tolerated and easy to take. The study will also assess its safety in women. The goal of this study is to determine whether dutasteride can provide a simple and effective way to prevent recurrences of low grade non-muscle invasive bladder cancer.
Protocol Amendment History 1 change
critical Recruitment opened 2026-03-31
Trial Details
NCT Number NCT07420517
Lead Sponsor Paul Toren
Conditions Bladder Cancer
Enrollment 95 participants
Start Date 2026-03-25
Primary Completion 2030-04-02 (estimated)
Study Completion 2032-04-02 (estimated)
Updated on ClinicalTrials.gov 2026-03-30