Clinical Trial

Remote Ischemic Preconditioning and Postoperative Neuronal Injury

Study acronym: SHIELD
Recruiting
View on ClinicalTrials.gov →
Summary
The SHIELD trial is a single-center, randomized, controlled, parallel-group, single-blinded clinical trial investigating whether performing RIPC one day before surgery-compared to not performing RIPC-reduces postoperative neuronal injury, as reflected by the maximum serum NfL concentration within the first 2 postoperative days, in non-cardiac surgery patients at risk for postoperative delirium.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-02-18.
Status change: Not Yet Recruiting → Recruiting 2026-03-02
Trial Details
NCT Number NCT07420153
Lead Sponsor University of Hamburg-Eppendorf
Conditions Postoperative Neuronal Injury
Enrollment 216 participants
Start Date 2026-03-02
Primary Completion 2027-08 (estimated)
Study Completion 2027-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-04