Older Kidney Patient Optimisation Pretransplant

The goal of this clinical trial is to learn if a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve the way older adults are assessed for kidney transplantation. The main questions it aims to answer are: Is it feasible and acceptable to deliver a KT-CGA alongside routine transplant assessment in older adults with advanced kidney disease? What is the effect of KT-CGA on decision-making about transplant listing and on patient-reported outcomes such as quality of life and frailty? Researchers will compare participants who receive the KT-CGA plus usual care to those who receive usual care alone. Participants will: Continue with their usual transplant assessment process If randomised to the intervention group, also complete the KT-CGA (a structured set of questionnaires, short memory and function tests, and discussions about wellbeing and support needs, taking about 45-60 minutes)

NCT Number	NCT07419945
Lead Sponsor	Guy's and St Thomas' NHS Foundation Trust Collaborators: King's College London
Conditions	Kidney Disease, Kidney Failure, Frailty, Cognitive Impairment, Multimorbidity, End Stage Kidney Disease (ESRD), Kidney Transplant, Health Inequity
Enrollment	50 participants
Start Date	2026-02-02
Primary Completion	2027-02-02 (estimated)
Study Completion	2028-02-02 (estimated)
Updated on ClinicalTrials.gov	2026-02-19