This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.

In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time. During the study, participants will attend scheduled visits where researchers will assess muscle strength, physical function, and overall health. Blood samples may be collected to measure markers related to metabolism, inflammation, and oxidative stress. Study staff will also monitor safety and any side effects throughout the study.

NCT Number	NCT07419633
Lead Sponsor	McGill University Health Centre/Research Institute of the McGill University Health Centre
Conditions	Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health, Ageing
Enrollment	120 participants
Start Date	2026-03-06
Primary Completion	2027-02-05 (estimated)
Study Completion	2027-02-05 (estimated)
Updated on ClinicalTrials.gov	2026-05-14