Technology-supported Motor Rehabilitation for People With Rett Syndrome

This study focuses on improving purposeful arm use while simultaneously reducing engagement in stereotypies. It is typically expected that the training period for this study will last about 6 months. The first half of the training periods will be devoted to learning to separate hands to stop the stereotypies that interfere with arm and hand use. In this first half, participants will also need to learn to keep arms apart in order to be actively involved in the chosen game. The second half of the training period will be devoted to learning to stop stereotypies and reach for targets that are intended to start game play. When not touching the targets, the software will interpret that the game should stop and wait for the next target to be touched.

NCT Number	NCT07418905
Lead Sponsor	Georgetown University Collaborators: Fraunhofer Heinrich Hertz Institut (HHI), Max-Planck-Institute for Cognition, Charite University, Berlin, Germany, Rett Syndrome of Germany
Conditions	Rett Syndrome
Enrollment	14 participants
Start Date	2024-10-01
Primary Completion	2026-07-31 (estimated)
Study Completion	2026-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-20