Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic Pancreatitis

This project uses the Malabsorption Blood Test (MBT) to identify patients with recurrent acute or chronic pancreatitis who have mild to moderate exocrine pancreatic insufficiency. A subgroup of patients who have response to pancreatic enzyme replacement therapy will enter a randomized, placebo-controlled pilot clinical trial for 8 weeks to identify improvements in quality of life (QOL).

NCT Number	NCT07418593
Lead Sponsor	Anna Evans Phillips Collaborators: Johns Hopkins University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Children's Hospital of Philadelphia, Digestive Care, Inc.
Conditions	Chronic Pancreatitis, Recurrent Acute Pancreatitis, Exocrine Pancreatic Insufficiency
Enrollment	80 participants
Start Date	2026-04-20
Primary Completion	2028-06 (estimated)
Study Completion	2028-09 (estimated)
Updated on ClinicalTrials.gov	2026-04-27