Clinical Trial

Clean Air for Rare MUcociliary Clearance dIsorders

Study acronym: CARMUCI
Enrolling by Invitation
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Summary
The goal of this clinical trial is to learn whether using a high efficiency particulate air (HEPA) air purifier can improve respiratory health in children and adults with Cystic Fibrosis (CF) or Primary Ciliary Dyskinesia (PCD). The main questions it aims to answer are: Can using a HEPA air purifier at home reduce respiratory symptoms in people with CF or PCD? Can it improve lung function and overall health? Researchers will compare participants' health outcomes before and after the use of the HEPA air purifier to see if cleaner indoor air makes a measurable difference. Participants will: Visit the clinic for baseline health assessments (such as lung function and symptom questionnaires). Have two HEPA air purifiers installed in their home. One device will be placed in the main living area and one in the bedroom. Undergo exposure assessments during home visits to measure indoor air quality.
Trial Details
NCT Number NCT07417267
Lead Sponsor University of Cyprus
Collaborators: Horizon 2020 - European Commission
Conditions Primary Ciliary Dyskinesia (PCD), Cystic Fibrosis (CF)
Enrollment 62 participants
Start Date 2025-05-01
Primary Completion 2027-04 (estimated)
Study Completion 2027-04 (estimated)
Updated on ClinicalTrials.gov 2026-02-18