Lower Respiratory Tract Infections Managed in Primary Care in France

Primary aim: To describe participant characteristics at the time of the index lower respiratory tract infection (LRTI) episode in adults managed in primary care in France, using anonymized electronic health records from routine clinical practice between January 2015 and December 2024. Secondary aims: To describe and quantify patterns of antibiotic prescribing (rate, type, and duration of treatment) and short-term outcomes, including LRTI-related reconsultations and severe complications within 30 days after the index consultation. The overall objective is to better characterize real-world management and outcomes of lower respiratory tract infections in primary care and to identify potential areas for improving quality of care and optimizing antibiotic stewardship.

NCT Number	NCT07416266
Lead Sponsor	Hôpital Raymond Poincaré Collaborators: Versailles Saint-Quentin-en-Yvelines University, University of Lausanne Hospitals, Clinityx by Gers Data
Conditions	Lower Respiratory Tract Infections, Community Acquired Pneumonia (CAP), Acute Bronchitis, Acute Exacerbation Chronic Obstructive Pulmonary Disease, Influenza
Enrollment	230,066 participants
Start Date	2015-01-01
Primary Completion	2024-12-31 (estimated)
Study Completion	2026-01-09 (estimated)
Updated on ClinicalTrials.gov	2026-02-18