Comparing PTeye-assisted Versus Conventional Total Thyroidectomy

This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH). The study will enroll consecutive patients undergoing total thyroidectomy in a teritary endocrine surgery unit in Hong Kong, randomizing them into receiving conventional surgery versus PTeye™-assisted surgery. Subjects will be assigned to the two groups before surgery. Subjects will be under medical care as in usual practice.

NCT Number	NCT07416149
Lead Sponsor	The University of Hong Kong
Conditions	Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy
Enrollment	210 participants
Start Date	2025-09-16
Primary Completion	2028-10-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-17