Clinical Trial

Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning

Study acronym: MENTOR
Recruiting
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Summary
With this project, the study group wants to investigate whether a postoperative navigated transcranial magnetic stimulation (nTMS) motor map can improve stereotactic radiosurgery (SRS) planning in patients who underwent resection for a brain metastasis near the primary motor cortex. Specifically, the map could allow for more precise location of motor eloquent tissue, thereby minimizing the radiation dose on these areas while preserving high radiation dose on target tissue (i.e. tumor cells).
Protocol Amendment History 2 changes
critical Recruitment opened 2026-04-30
critical Primary endpoint(s) modified 2026-04-30
Trial Details
NCT Number NCT07415668
Lead Sponsor Insel Gruppe AG, University Hospital Bern
Conditions Metastases to Brain
Enrollment 30 participants
Start Date 2026-05-08
Primary Completion 2029-04-30 (estimated)
Study Completion 2029-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-04