PPV vs PVI in the Supine and Prone Position

This is a prospective study that will record the Pulse Pressure Variability (PPV) from the arterial line and Plethysmography Variability Index (PVI) from the pulse oximeter while the patient is in the supine position and then again in the prone position. There will be no change in anesthetic care based on the study protocol. The primary objective of this study is to evaluate the changes in PVI and PPV when changing from the supine and prone position in pediatric-aged patients.

NCT Number	NCT07415603
Lead Sponsor	Joseph D. Tobias
Conditions	Surgeries Undergoing General Anesthesia
Enrollment	100 participants
Start Date	2026-06
Primary Completion	2029-05-31 (estimated)
Study Completion	2029-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-17