Clinical Trial

Oxygen Reserve Index (ORi) in Identifying Desaturation

Not Yet Recruiting
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Record status
This record was last updated February 17, 2026 (before its estimated March 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized clinical trial investigates whether Oxygen Reserve Index (ORi) monitoring enables earlier detection of impending hypoxemia compared with conventional pulse oximetry during apneic intermittent ventilation in adult patients undergoing endolaryngeal surgery under general anesthesia. By providing continuous, noninvasive assessment of oxygen reserve in the hyperoxic range, ORi may offer an earlier warning of oxygen depletion before peripheral oxygen saturation declines. The study compares time to reventilation thresholds, arterial blood gas parameters, and perioperative respiratory outcomes between ORi-guided and standard SpO₂-guided monitoring strategies.
Trial Details
NCT Number NCT07415161
Lead Sponsor Istanbul University
Conditions Apneic Oxygenation, Endolarengeal Surgery, Oxygen Reserve Index
Enrollment 80 participants
Start Date 2026-01-27
Primary Completion 2026-03-15 (estimated)
Study Completion 2026-03-25 (estimated)
Updated on ClinicalTrials.gov 2026-02-17