Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages

The study is meant to run parallel to the larger study, RESET. The goal of this study is to to evaluate the effectiveness of a once-off general and personality-tailored text message on GP consultation among RESET participants identified to have high LDL-C. The main question it aims to answer is: Will participants exposed to personality tailored advice have a higher adherence to GP consultation compared to the participants in the control group? Researchers will compare a personalized message to a general message (with no personalization according to patients personality type) and control group to see if the messages increase adherence. Participants are required to complete two questionnaires: one before and one after they receive their RESET results.

NCT Number	NCT07415109
Lead Sponsor	National University Health System, Singapore
Conditions	Adherence, Preventive Health Services
Enrollment	3,000 participants
Start Date	2025-11-25
Primary Completion	2028-01 (estimated)
Study Completion	2028-11 (estimated)
Updated on ClinicalTrials.gov	2026-04-13