The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.

This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence. The goal is to assess improvements in tissue integration and the reduction of surgical complications

NCT Number	NCT07414849
Lead Sponsor	Hospital General de Agudos J. M. Penna
Conditions	Pelvic Organ Prolapse Vaginal Surgery, Stress Urinary Incontinence in Women
Enrollment	330 participants
Start Date	2026-03-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-17