Clinical Trial

Variability of Microwave Ablation Volume Based on Clinical, Radiological, Biological, and Tissue Factors

Study acronym: MICRO-VAR
Recruiting
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Record status
This record was last updated February 25, 2026 (before its estimated July 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Microwave ablation is a minimally invasive technique whose planning relies on manufacturer tables derived from ex vivo models that do not account for patient or tumor-specific factors. In clinical practice, the actual ablation volume often differs from the planned volume due to liver characteristics, vascular proximity, and tumor biology. This study aims to assess the variability between ablation small axis during percutaneous microwave ablation of liver lesions. The influence of patient-related (fibrosis, steatosis, portal flow) and tumor-related factors (location, histology, prior treatment) will be evaluated. Small axis and volume will be compared with volumes measured on immediate post-procedural CT and on CT/MRI at 6-12 weeks, accounting for expected tissue shrinkage.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-02-09.
Trial Details
NCT Number NCT07413640
Lead Sponsor Central Hospital, Nancy, France
Conditions Liver Neoplasm
Enrollment 90 participants
Start Date 2026-02-02
Primary Completion 2026-07-01 (estimated)
Study Completion 2026-07-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-25