Clinical Trial

Spinal Cord Stimulation Combined With Motor Training in Non-Traumatic SCI: A Prospective Interventional Study

Study acronym: Neuro-scs-002
Not Yet Recruiting
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Summary
Interventional prospective longitudinal on the evaluation of spinal cord stimulation (SCS) assisted by motor rehabilitation training for restoring motor function in patients with non-traumatic spinal cord injury (SCI). The investigators will enroll ten research participants with clinically incomplete/complete SCI (patients with paraplegia or severe paraparesis) who will undergo SCS subsequently assisted by motor rehabilitation training for restoring motor function at IRCCS Ospedale San Raffaele, Milan, Italy. The main goal of the project is to evaluate the improvement in motor function generated by the combination of SCS and locomotor training. In line with recently published studies, the investigators propose that daily locomotor training in the presence of SCS with continuous stimulation parameters setting will enable the SCI individuals to stand and step independently while bearing full weight.
Trial Details
NCT Number NCT07412808
Lead Sponsor Albano Luigi
Collaborators: Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Conditions Spinal Cord Disease, Spinal Cord Injuries (Complete and Incomplete)
Enrollment 10 participants
Start Date 2026-03
Primary Completion 2028-04 (estimated)
Study Completion 2029-04 (estimated)
Updated on ClinicalTrials.gov 2026-02-17