Non-Surgical Periodontal Therapy and Cardiac Biomarkers in Stable Angina

The goal of this clinical study is to learn whether gum treatment can improve heart health. Researchers will compare blood markers related to heart disease before and after routine gum treatment. The main questions this study aims to answer are: Is gum disease a risk factor for heart disease? Can treating gum disease lower the risk of heart disease? Adults with stable angina (a type of heart disease) and adults without heart disease may take part in this study. All participants will receive routine, non-surgical gum treatment, which is a standard dental care procedure. This includes professional cleaning to remove plaque and tartar from the teeth and practical education on tooth brushing and cleaning between the teeth. The treatment will be performed by a single researcher and completed in one visit within about one hour. Participants will: Provide a blood sample before gum treatment Receive routine, non-surgical gum treatment Return after three months for a follow-up visit Provide a second blood sample This study does not involve experimental drugs or devices. Participation is voluntary, and there is no cost to participants. The results may help researchers better understand how gum health is related to heart health.

NCT Number	NCT07412795
Lead Sponsor	Ondokuz Mayıs University
Conditions	Stable Angina, Periodontitis
Enrollment	60 participants
Start Date	2026-02-20
Primary Completion	2026-06-05 (estimated)
Study Completion	2026-08-05 (estimated)
Updated on ClinicalTrials.gov	2026-02-17